After Dong Zhuo died by his adoptive son Lü Bu by an assassination plot by Wang Yun. He along with Li Jue, Guo Si, and Zhang Ji defeated Lü Bu then defeated Wang Yun, which they taken over Chang'an and the young Emperor Xian. Once Li Jue and Guo Si wanted to kill the emperor, but Fan Chou and Zhang Ji calmed them down, saying that they should control the emperor like Dong Zhuo did.
Later, he enjoyed successes when Ma Teng and Han Sui attacked Chang'an, but on one occasion he allowed Han Sui, his fellow townsman, to go unharmed and talked amiably with him. When Li Jue knew of this, he had Fan Chou executed.
A Qing Dynasty illustration showing the execution of Fan Chou.