Feline spongiform encephalopathy
Feline spongiform encephalopathy (FSE) is a prion disease thought to be related or identical to Bovine spongiform encephalopathy (BSE).This disease is known to affect domestic and captive feline species. Lezmi S. et al. (2003), suggested that this infectious agent might be spread by both haematogenous and nervous pathways. Like BSE, this disease can take several years to develop. It is probable, but not proven, that the affected animals contract the disease by eating contaminated bovine meat.
This disease was first reported in domestic cats within the United Kingdom in 1990. Since 1990, cases have been reported in other countries and other feline species in captivity have been reported to have contracted this disease.
This disease can only be confirmed at the post-mortem, which includes identification of bilaterally symmetrical vacuolation of the neuropil and vacuolation in neurones. Lesions are likely to be found in basal ganglia, cerebral cortex and thalamus of the brain.
- Iulini, B; Cantile, C; Mandara, MT; Maurella, C; Loria, GR; Castagnaro, M; Salvadori, C; Porcario, C; Corona, C; Perazzini, AZ; Maroni, A; Caramelli, M; Casalone, C. "Neuropathology of italian cats in feline spongiform encephalopathy surveillance.". Vet Pathol. 45: 626–33. doi:10.1354/vp.45-5-626. PMID 18725465.
- "PROVET HEALTHCARE INFORMATION - FELINE SPONGIFORM ENCEPHALOPATHY (FSE)".
- "Possible Case of Maternal Transmission of Feline Spongiform Encephalopathy in a Captive Cheetah". doi:10.1371/journal.pone.0006929.
- "Biochemical and immunohistochemical characterization of feline spongiform encephalopathy in a German captive cheetah" (PDF). doi:10.1099/vir.0.022103-0.
- "Mad Cow Disease and Cats". College of Veterinary Medicine, Cornell University. 15 Nov 2006.
- "ARCHIVE: BSE: Other TSEs".
- "First case of feline spongiform encephalopathy in a captive cheetah born in France: PrPsc analysis in various tissues revealed unexpected targeting of kidney and adrenal gland". doi:10.1007/s00418-003-0524-5.
|This veterinary medicine–related article is a stub. You can help Wikipedia by expanding it.|