Fenamic acid

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Fenamic acid
Fenamic acid.png
Ball-and-stick model of fenamic acid
Names
IUPAC name
2-(phenylamino)benzoic acid
Other names
N-phenylanthranilic acid
Identifiers
91-40-7 YesY
ChEBI CHEBI:34756 N
ChEMBL ChEMBL23832 N
4182
Jmol-3D images Image
PubChem 4386
Properties
C13H11NO2
Molar mass 213.23 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 N verify (what isYesY/N?)
Infobox references

Fenamic acid is a molecule which, especially in its ester form, fenamate,[1]:458 serves as a parent structure for several non-steroidal anti-inflammatory drugs, including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid. These drugs are commonly referred to as "anthranilic acid derivatives" or "fenamates" because fenamic acid is a derivative of anthranilic acid,[2]:235[3]:17 which in turn is a nitrogen isostere of salicylic acid.[2]

References[edit]

  1. ^ Gupta, PK. Drug NomenclatureUnited States Adopted Names. Ch 27 in Remington: The Science and Practice of Pharmacy, Vol 1. Eds. David B. Troy, Paul Beringer. Lippincott Williams & Wilkins, 2006 ISBN 9780781746731
  2. ^ a b Sriram D, Yogeeswari P. Medicinal Chemistry, 2nd Edition. Pearson Education India, 2010. ISBN 9788131731444
  3. ^ Auburn University course material. Jack DeRuiter, Principles of Drug Action 2, Fall 2002 1: Non-Steroidal Antiinflammatory Drugs (NSAIDS)