Fenbufen

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Fenbufen
Fenbufen.svg
Fenbufen-from-xtal-1988-3D-balls.png
Systematic (IUPAC) name
4-(4-Biphenylyl)-4-oxobutanoic acid
or
4-Oxo-4-(4-phenylphenyl)butanoic acid
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
  • POM
Routes of
administration
Oral
Identifiers
CAS Number 36330-85-5
ATC code M01AE05
PubChem CID 3335
DrugBank DB08981 YesY
ChemSpider 3218 YesY
UNII 9815R1WR9B YesY
KEGG D01344 YesY
ChEBI CHEBI:31599 YesY
ChEMBL CHEMBL277522 YesY
Chemical data
Formula C16H14O3
Molar mass 254.2854
  (verify)

Fenbufen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives class.[1]

It was introduced by American Cyanamid under the trade name Lederfen in the 1980s and was withdrawn from markets in the developed world due to liver toxicity in 2010.[2][3]:370, 383-384

As of 2015 is was available in Taiwan and Thailand under several brand names.[4]

References[edit]

  1. ^ Brogden RN. Non-steroidal anti-inflammatory analgesics other than salicylates. Drugs. 1986;32 Suppl 4:27-45. Review. PMID 3552584
  2. ^ Monthly Index of Medical Specialities Deleted products 2010
  3. ^ Lewis JH and Stine JG. Nonsteroidal Antiinflammatory Drugs and Leukotriene Receptor Antagonists. Chapter 22 in Drug-Induced Liver Disease, 3rd Edition. Eds Neil Kaplowitz N and DeLeve LD. Academic Press, 2013 ISBN 9780123878182
  4. ^ Drugs.com Drugs.com international listings for fenbufen Page accessed June 25, 2015