Fentiazac

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Fentiazac
Fentiazac.png
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Systematic (IUPAC) name
2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Registry Number 18046-21-4
ATC code M02AA14
PubChem CID: 28871
UNII 0YHF6E6NLS YesY
KEGG D01975 YesY
Chemical data
Formula C17H12ClNO2S
Molecular mass 329.80068 g/mol
Physical data
Melting point 162–163 °C (324–325 °F)
 YesY (what is this?)  (verify)

Fentiazac is a nonsteroidal antiinflammatory agent used for joint and muscular pain.

Synthesis[edit]

Thiobenzamide is reacted with 3-(4-chlorobenzoyl)-3-bromopropionic acid:

Synthesis of Fentiazac:[1]

References[edit]

  1. ^ Brown, K.; Cater, D. P.; Cavalla, J. F.; Green, D.; Newberry, R. A.; Wilson, A. B. (1974). "Nonsteroidal antiinflammatory agents. 1. 2,4-Diphenylthiazole-5-acetic acid and related compounds". Journal of Medicinal Chemistry 17 (11): 1177–1181. doi:10.1021/jm00257a010. PMID 4414839.