Fenticonazole

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Fenticonazole
Fenticonazole.svg
Clinical data
Trade names Lomexin, Gynoxin
AHFS/Drugs.com International Drug Names
Routes of
administration
Topical (ovule, spray, cream)
ATC code
Legal status
Legal status
  • UK: POM (Prescription only)
  • US: Not FDA approved
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
Chemical and physical data
Formula C24H20Cl2N2OS
Molar mass 455.4 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Fenticonazole is an imidazole antifungal drug, used locally as the nitrate in the treatment of vulvovaginal candidiasis. It is active against a range of organisms including dermatophyte pathogens, Malassezia furfur, and Candida albicans.

Uses and administration[edit]

A 200 mg pessary is inserted into the vagina at bedtime for 3 nights or a 600 mg pessary is inserted once only at bedtime. Fenticonazole nitrate is also applied topically as a 2% cream or solution for the treatment of fungal skin infections.

Adverse effects[edit]

Burning and itching have been reported after the application of fenticonazole nitrate.

Intravaginal preparations of fenticonazole may damage latex contraceptives and additional contraceptive measures are therefore necessary during local administration.

References[edit]

  • The Merck Index, 12th Edition. 4047