Ferredoxin hydrogenase

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ferredoxin hydrogenase
EC number
CAS number 9080-02-8
IntEnz IntEnz view
ExPASy NiceZyme view
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a ferredoxin hydrogenase (EC is an enzyme that catalyzes the chemical reaction

H2 + 2 oxidized ferredoxin 2 reduced ferredoxin + 2 H+

Thus, the two substrates of this enzyme are H2 and oxidized ferredoxin, whereas its two products are reduced ferredoxin and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is hydrogen:ferredoxin oxidoreductase. Other names in common use include H2 oxidizing hydrogenase, H2 producing hydrogenase [ambiguous], bidirectional hydrogenase, hydrogen-lyase [ambiguous], hydrogenase (ferredoxin), hydrogenase I, hydrogenase II, hydrogenlyase [ambiguous], and uptake hydrogenase [ambiguous]. This enzyme participates in glyoxylate and dicarboxylate metabolism and methane metabolism. It has 3 cofactors: iron, Sulfur, and Nickel.


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