File:GVHD initiation.jpeg

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Summary[edit]

An overview of an immune response during allogeneic stem cell transplantation: A SNP in the coding region of the recipient is polymorphic from the amino acid sequence of a donor's T cell. The T cell receptor specific for peptide and MHC molecule recognizes the self-peptide bound to the groove of HLA matched gene as forgein and initiates an immune response. The donor's CD8+ cell targets the recipient’s nucleated cell resulting in graft-versus-host disease.

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Date/TimeThumbnailDimensionsUserComment
current21:49, 8 February 2017Thumbnail for version as of 21:49, 8 February 2017720 × 540 (47 KB)Immcarle30 (talk | contribs)An overview of an immune response during allogeneic stem cell transplantation: A SNP in the coding region of the recipient DNA will be translated into protein and is polymorphic from the amino acid sequence of a donor's T cell. The T cell receptor spec...
19:18, 8 February 2017Thumbnail for version as of 19:18, 8 February 2017720 × 540 (45 KB)Immcarle30 (talk | contribs)An overview of an immune response during allogeneic stem cell transplantation: A SNP in the coding region of the recipient is polymorphic from the amino acid sequence of a donor's T cell. The T cell receptor specific for peptide and MHC molecule recog...
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