File:Histopathology of androgen insensitivity.jpg

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Histopathology_of_androgen_insensitivity.jpg(364 × 273 pixels, file size: 50 KB, MIME type: image/jpeg)

Summary[edit]

Description

Histopathology of testicular tissue showing immature germ cells and spermatagonia with decreased tubular diameter. Scattered groups of Leydig cells appearing immature.

Source

Nichols JL, Bieber EJ, Gell JS. Case of sisters with complete androgen insensitivity syndrome and discordant Müllerian remnants. Fertil Steril. 2009;91:932e15-e18.

Article

Androgen insensitivity syndrome

Portion used

Single image from an article in a medical journal.

Low resolution?

Resolution of this image will not affect journal subscriptions (i.e. revenue).

Purpose of use

This image illustrates the effects of androgen insensitivity on the cellular level. Individuals with PAIS are at a 50% germ cell malignancy risk because of these abnormalities, and must undergo surgical intervention (i.e. gonadectomy) to prevent metastatic cancer.

Replaceable?

AIS is a very rare disorder, affecting approximately 1 in 100,000 births. Images of this kind (histopathology illustrated by slide of testicular cells) from this population are not likely to exist outside of the medical literature, and thus the image is unlikely to be replaced by one from a free source.

Other information

A source that describes the incidence of germ cell malignancy among individuals with PAIS is Hughes IA, Houk C, Ahmed SF, Lee PA, LWPES Consensus Group, ESPE Consensus Gruop. Consensus statement on management of intersex disorders. Arch Dis Child. 2006;91:554-63. Sources that describe PAIS and its rarity include: (1:) Quigley CA, De Bellis A, Marschke KB, El-Awady MK, Wilson EM, French FS. Androgen receptor defects: historical, clinical, and molecular perspectives. Endocr Rev. 1995;16:271–321. (2:)Mazen I, El-Ruby M, Kamal R, El-Nekhely I, El-Ghandour M, Tantawy S, El-Gammal M. Screening of Genital Anomalies in Newborns and Infants in Two Egyptian Governorates. Horm Res Paediatr. 2010;73:438-442.

Fair useFair use of copyrighted material in the context of Androgen insensitivity syndrome//en.wikipedia.org/wiki/File:Histopathology_of_androgen_insensitivity.jpgtrue
Description

Histopathology of testicular tissue showing immature germ cells and spermatagonia with decreased tubular diameter. Scattered groups of Leydig cells appearing immature.

Source

Nichols JL, Bieber EJ, Gell JS. Case of sisters with complete androgen insensitivity syndrome and discordant Müllerian remnants. Fertil Steril. 2009;91:932e15-e18.

Article

Mild androgen insensitivity syndrome

Portion used

Single image from an article in a medical journal.

Low resolution?

Resolution of this image will not affect journal subscriptions (i.e. revenue).

Purpose of use

This image illustrates the effects of androgen insensitivity on the cellular level. Individuals with PAIS are at a 50% germ cell malignancy risk because of these abnormalities, and must undergo surgical intervention (i.e. gonadectomy) to prevent metastatic cancer.

Replaceable?

MAIS is a very rare disorder, affecting fewer than 1 in 100,000 births. Images of this kind (histopathology illustrated by slide of testicular cells) from this population are not likely to exist outside of the medical literature, and thus the image is unlikely to be replaced by one from a free source.

Other information

A source that describes the incidence of germ cell malignancy among individuals with PAIS is Hughes IA, Houk C, Ahmed SF, Lee PA, LWPES Consensus Group, ESPE Consensus Gruop. Consensus statement on management of intersex disorders. Arch Dis Child. 2006;91:554-63. Sources that describe PAIS and its rarity include: (1:) Quigley CA, De Bellis A, Marschke KB, El-Awady MK, Wilson EM, French FS. Androgen receptor defects: historical, clinical, and molecular perspectives. Endocr Rev. 1995;16:271–321. (2:)Mazen I, El-Ruby M, Kamal R, El-Nekhely I, El-Ghandour M, Tantawy S, El-Gammal M. Screening of Genital Anomalies in Newborns and Infants in Two Egyptian Governorates. Horm Res Paediatr. 2010;73:438-442.

Fair useFair use of copyrighted material in the context of Mild androgen insensitivity syndrome//en.wikipedia.org/wiki/File:Histopathology_of_androgen_insensitivity.jpgtrue
Description

Histopathology of testicular tissue showing immature germ cells and spermatagonia with decreased tubular diameter. Scattered groups of Leydig cells appearing immature.

Source

Nichols JL, Bieber EJ, Gell JS. Case of sisters with complete androgen insensitivity syndrome and discordant Müllerian remnants. Fertil Steril. 2009;91:932e15-e18.

Article

Partial androgen insensitivity syndrome

Portion used

Single image from an article in a medical journal.

Low resolution?

Resolution of this image will not affect journal subscriptions (i.e. revenue).

Purpose of use

This image illustrates the effects of androgen insensitivity on the cellular level. Individuals with PAIS are at a 50% germ cell malignancy risk because of these abnormalities, and must undergo surgical intervention (i.e. gonadectomy) to prevent metastatic cancer.

Replaceable?

PAIS is a very rare disorder, affecting approximately 1 in 100,000 births. Images of this kind (histopathology illustrated by slide of testicular cells) from this population are not likely to exist outside of the medical literature, and thus the image is unlikely to be replaced by one from a free source.

Other information

A source that describes the incidence of germ cell malignancy among individuals with PAIS is Hughes IA, Houk C, Ahmed SF, Lee PA, LWPES Consensus Group, ESPE Consensus Gruop. Consensus statement on management of intersex disorders. Arch Dis Child. 2006;91:554-63. Sources that describe PAIS and its rarity include: (1:) Quigley CA, De Bellis A, Marschke KB, El-Awady MK, Wilson EM, French FS. Androgen receptor defects: historical, clinical, and molecular perspectives. Endocr Rev. 1995;16:271–321. (2:)Mazen I, El-Ruby M, Kamal R, El-Nekhely I, El-Ghandour M, Tantawy S, El-Gammal M. Screening of Genital Anomalies in Newborns and Infants in Two Egyptian Governorates. Horm Res Paediatr. 2010;73:438-442.

Fair useFair use of copyrighted material in the context of Partial androgen insensitivity syndrome//en.wikipedia.org/wiki/File:Histopathology_of_androgen_insensitivity.jpgtrue
Description

Histopathology of testicular tissue showing immature germ cells and spermatagonia with decreased tubular diameter. Scattered groups of Leydig cells appearing immature.

Source

Nichols JL, Bieber EJ, Gell JS. Case of sisters with complete androgen insensitivity syndrome and discordant Müllerian remnants. Fertil Steril. 2009;91:932e15-e18.

Article

Complete androgen insensitivity syndrome

Portion used

Single image from an article in a medical journal.

Low resolution?

Resolution of this image will not affect journal subscriptions (i.e. revenue).

Purpose of use

This image illustrates the effects of androgen insensitivity on the cellular level. Individuals with PAIS are at a 50% germ cell malignancy risk because of these abnormalities, and must undergo surgical intervention (i.e. gonadectomy) to prevent metastatic cancer.

Replaceable?

CAIS is a very rare disorder, affecting approximately 1 in 20,000 births. Images of this kind (histopathology illustrated by slide of testicular cells) from this population are not likely to exist outside of the medical literature, and thus the image is unlikely to be replaced by one from a free source.

Other information

A source that describes the incidence of germ cell malignancy among individuals with PAIS is Hughes IA, Houk C, Ahmed SF, Lee PA, LWPES Consensus Group, ESPE Consensus Gruop. Consensus statement on management of intersex disorders. Arch Dis Child. 2006;91:554-63. Sources that describe PAIS and its rarity include: (1:) Quigley CA, De Bellis A, Marschke KB, El-Awady MK, Wilson EM, French FS. Androgen receptor defects: historical, clinical, and molecular perspectives. Endocr Rev. 1995;16:271–321. (2:)Mazen I, El-Ruby M, Kamal R, El-Nekhely I, El-Ghandour M, Tantawy S, El-Gammal M. Screening of Genital Anomalies in Newborns and Infants in Two Egyptian Governorates. Horm Res Paediatr. 2010;73:438-442.

Fair useFair use of copyrighted material in the context of Complete androgen insensitivity syndrome//en.wikipedia.org/wiki/File:Histopathology_of_androgen_insensitivity.jpgtrue

Licensing[edit]

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Date/TimeThumbnailDimensionsUserComment
current06:34, 29 November 2017Thumbnail for version as of 06:34, 29 November 2017364 × 273 (50 KB)Theo's Little Bot (talk | contribs)Reduce size of non-free image (BOT - disable)
23:10, 19 September 2010No thumbnail438 × 329 (208 KB)Jonathan.Marcus (talk | contribs){{Non-free use rationale |Article = Androgen insensitivity syndrome |Description = Histopathology of testicular tissue showing immature germ cells and spermatagonia with decreased tubular diameter. Scattered groups of Leydig cells appea
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