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File:SEM - range of α and β− particles.jpg

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Summary

Description
English: The favorable geometric situation for α-particles in small-scale metastases (e.g., in the adjuvant setting) is depicted in a scanning electron microscopy micrograph of micro-metastatic clusters from ovarian cancer on the peritoneal lining (mouse). The range of the α-particles in red (here ~50–70 μm), can hardly reach the surrounding normal healthy cells other than possibly the mesothelium and its sub-layer. They cannot reach the epithelial cells of the intestinal lining. The situation for β− particles on the other hand, shows that a great deal of its energy will be deposited far away from the binding site and possibly into healthy tissue as demonstrated by the white dashed line (here ~700 μm). Consequently, it may add to side effects. Bar equals 100 μm.
Date
Source (2014). "The Potential and Hurdles of Targeted Alpha Therapy – Clinical Trials and Beyond". Frontiers in Oncology 3. DOI:10.3389/fonc.2013.00324. PMC: 3890691.
Author Jörgen Elgqvist, Sofia Frost, Jean-Pierre Pouget and Per Albertsson

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current19:08, 19 December 2016Thumbnail for version as of 19:08, 19 December 20161,323 × 489 (349 KB)BeevilUser created page with UploadWizard
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