Flavoxate

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Flavoxate
Flavoxate.svg
Clinical data
AHFS/Drugs.com Monograph
MedlinePlus a682706
ATC code
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard 100.035.745
Chemical and physical data
Formula C24H25NO4
Molar mass 391.46 g/mol
3D model (JSmol)
 NYesY (what is this?)  (verify)

Flavoxate is an anticholinergic with antimuscarinic effects. Its muscle relaxant properties may be due to a direct action on the smooth muscle rather than by antagonizing muscarinic receptors.

Clinical uses[edit]

Flavoxate is used to treat urinary bladder spasms. It is available under the trade name Urispas (Paladin), Genurin (by Recordati, Italy) in Italy and KSA, Uritac by El Saad company in Syria, under the name Bladderon by Nippon Shinyaku of Japan, or Bladuril in Chile, Utispas ( Apex Pharma) in Nepal.

Flavoxate is indicated for symptomatic relief of interstitial cystitis, dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.

Side effects[edit]

Flavoxate is generally well tolerated, but can potentially cause, vomiting, upset stomach, dry mouth or throat, blurred vision, eye pain,[1] and increased sensitivity of your eyes to light.

Contraindications[edit]

Flavoxate is contraindicated in patients who have any of the following obstructive conditions: pyloric or duodenal obstruction, obstructive intestinal lesions or ileus, achalasia, gastrointestinal hemorrhage and obstructive uropathies of the lower urinary tract.

See also[edit]

Notes[edit]

  1. ^ Zakir SM, Zaka-ur-Rab S, Salman MT, Khan RA. Bilateral acute angle closure glaucoma in a 50-year-old female after oral administration of flavoxate. British Journal of Clinical Pharmacology. 2008. 66(5):726-727

References[edit]