Fleischer ring

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Fleischer rings are pigmented rings in the peripheral cornea, resulting from iron deposition[1] in basal epithelial cells, in the form of hemosiderin.[2] They are usually yellowish to dark-brown, and may be complete or broken.

They are named for Bruno Fleischer.[3]

Fleischer rings are indicative of keratoconus,[4] a degenerative corneal condition that causes the cornea to thin and change to a conic shape.

Confusion with Kayser-Fleischer rings[edit]

Some confusion exists between Fleischer rings and Kayser-Fleischer rings. Kayser-Fleischer rings are caused by copper deposits, and are indicative of Wilson's disease, whereas Fleischer rings are caused by iron deposits. One example of a medical condition that can present with Fleischer rings is Keratoconus.

See also[edit]

Other iron lines:


  1. ^ "Cornea & External Diseases-Keratoconus Fleischer's Ring". Retrieved 2008-10-24. 
  2. ^ "Definition: Fleischer's ring from Online Medical Dictionary". Retrieved 2008-10-24. 
  3. ^ Fleischer, B (1906). "Über Keratokonus und eigenartige Pigmentbildung in der Kornea". Münchener medizinische Wochenschrift. 53: 625–626. 
  4. ^ Hiratsuka Y, Nakayasu K, Kanai A (2000). "Secondary keratoconus with corneal epithelial iron ring similar to Fleischer's ring". Japanese Journal of Ophthalmology. 44 (4): 381–6. doi:10.1016/S0021-5155(00)00179-9. PMID 10974294.