Flightless fruit fly

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

Flightless fruit flies (Order Diptera) encompasses a variety of different species of fly, such as Drosophila melanogaster, Bactrocera cucurbitae, Bactrocera dorsalis, and Drosophila hydei, with genetic mutations that cause them to be flightless.[1] These genetic mutations may have different results such as the development of muscles that cannot support flight or even result in the lack of wings entirely.[2] Flightless fly models have been especially useful for the study of human neuromuscular diseases such as spinal muscular atrophy, spinobulbar muscular atrophy, myotonic dystrophy, dystrophinopathies and other inherited neuromuscular diseases.[3][4] Other applications of flightless flies include using them as convenient feeders for a variety of companion animals[5] and even as test subjects in aeronautical research [6]


  1. ^ Lloyd, T. E. and Taylor, J. P. (2010), Flightless flies: Drosophila models of neuromuscular disease. Annals of the New York Academy of Sciences, 1184: E1–E20. doi: 10.1111/j.1749-6632.2010.05432.x
  2. ^ McCOMBS, SUSAN D.; SAUL, STEPHEN H. Flightless Mutants in the Melon Fly and Oriental Fruit Fly (Diptera: Tephritidae) and Their Possible Role in the Sterile Insect Release Method. Annals of the Entomological Society of America, Volume 85, Number 3, May 1992, pp. 344-347(4)
  3. ^ Rajendra, T.K. et al . 2007. A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle. J. Cell Biol. 176: 831–841.
  4. ^ Bloomquist, J. R. and Miller, T. A. (1986), Neural correlates of flight activation and escape behavior in houseflies recovering from pyrethroid poisoning. Arch. Insect Biochem. Physiol., 3: 551–559. doi: 10.1002/arch.940030606.
  5. ^ "ALL ABOUT FLIGHTLESS FRUIT FLIES." The Fruit Fly Shop. Web 29 May 2013.
  6. ^ Kathy Barnstorff. "FRUIT FLIES IMPROVING FLIGHT." 15 May 2013 NASA. Web 30 May 2013.