Born as Florence Ann Brumby in Longford, Tasmania, she moved to Sydney, where she married George Reid in 1891. He was 46 years old, she 23 years old. They had three children. She became a member of the Women's Federal League, but otherwise focused on raising her family.
Husband, Sir George Reid
Her husband was prime minister from 1904 to 1905. Upon his first knighthood in 1909, she became Lady Reid (he had further knighthoods in 1911 and 1916). She accompanied her husband to London in 1910 on his appointment as the first Australian High Commissioner to the United Kingdom. He was also a member of the United Kingdom House of Commons from 1916 to 1918.
For her work in assisting Australian soldiers recuperating in London from World War I, she was appointed a Dame Grand Cross of the Order of the British Empire (GBE) in August 1917, being in the first list of appointments to the order, which had been created only in June 1917.
Sir George Reid died in 1918, aged 73, and was buried in London. Dame Flora Reid died on 1 September 1950 in Rose Bay, New South Wales, aged 82.