Florence Comite

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Florence Comite, MD
FComite - Headshot.jpg
Dr. Florence Comite
Born Florence Comite
Nationality American
Occupation Medical Doctor
Employer ComiteMD, Northwell Health[1]
Known for Associate Clinical Professor Yale University School of Medicine
Title Endocrinologist
Website Official website

Dr. Florence Comite is an endocrinologist[2] who has helped develop new therapies for osteoporosis, endometriosis, fibroid disease, and infertility.[3] She is known for patent approval for developing a new method of determining fertility in women[4] In 1990, Dr. Comite was awarded a second patent for the use of clomifene to increase bone mass in premenopausal women.[5]

Field of study[edit]

Dr. Comite is known for having an integrated approach to health care delivery using precision medicine.[6][7] She has done extensive research on hormonal changes and aging, and in particular, issues of Hypogonadism (Low T) in men and how it impacts the onset of certain associated diseases such as type 2 diabetes, heart disease.[8]

Her research involves studying delivery systems and how they impact health outcomes; it has been her focus as a Senior Clinical and Research Adviser to the Offices of Alternative Medicine (OAM) at NIH.[9]


In addition to her research, Comite's practice in New York City is based on a philosophical concept of the innate uniqueness of each human. Her method begins with the collecting of data on a patient to address the individual’s status via what Comite refers to as a precision health analysis.[10][11] Dr. Comite’s focus is on personalized treatment paths based on customized tracts incorporating unique aspects for each patient based on a myriad of variables such as lifestyle, metabolism, hormonal and genetic factors, in conjunction with evidence-based medicine to help patients best manage their aging process.[12] Comite also works on helping males deal with what she refers to as Male Menopause.[13][14]

Education and early career[edit]

Comite graduated Summa Cum Laude from Brooklyn College of the City University of New York Yale University School of Medicine;[4] she was an Associate Clinical Professor on the Yale faculty for 25 years; as a leader in women's health for over 15 years, she first founded Women's Health at Yale in 1988.[15] Dr. Comite completed a fellowship in Reproductive Endocrinology, incorporating training in Medicine, Pediatrics, Gynecology and Andrology,[14] at the National Institute of Child Health and Human Development at NIH. In the early 1980, she was researching the use of Gonadotropin-releasing hormones to treat precocious puberty.[16][17]

Comite had researched in the area of complementary and alternative medicine (CAM),[18] and was recognized by the National Academy of Science's Institute of Medicine's (IOM), where she was elected to the IOM’s Complementary and Alternative Medicine Committee in 2003.

Dr. Comite has served on advisory councils and committees with the NIH, the Egyptian Ministry of Health, and on the Balance Documentary Medical Advisory Board,[19] the Age Management Medicine Group, Independent Doctors of New York,[20] and the American Fertility Society as well as Alpha Omega Alpha.[21]

Awards and recognition[edit]

Dr. Comite won the Salk scholarship award for original research at Brooklyn College, the Louis Welt Award at Yale Medical School, the Alan P. Mintz, MD Award for Clinical Excellence in Age Management Medicine,[15] and has been the recipient of additional awards for original research throughout her career.[22]


Comite has been published in the New England Journal of Medicine,[23] and the Journal of Clinical Endocrinology and Metabolism.[24]

In June 2013 Comite published a work focused on male menopause, entitled: “Hormonal Expression of Androgen Deficiency in Aging Men (ADAM),”[11] the findings were presented at the Endocrine Society in San Francisco.


  1. ^ "Florence Comite, MD". Northwell Health. 
  2. ^ "Male Menopause Crisis Finds Solutions In Hormone Optimization Program". Red Orbit. 24 April 2007. Retrieved 2 April 2014. 
  3. ^ "Complementary and Alternative Medicine in the United States: Committee members". National Center for Biotechnology Information, U.S. National Library of Medicine. National Institute for Health. Retrieved 2 April 2014. 
  4. ^ a b using clomifene.Andrews, Edmund (29 April 1989). "Patents; A Method to Determine Fertility in Women". New York Times. Retrieved 2 April 2014. 
  5. ^ Yale, University. "Use of clomiphene to increase bone mass in premenopausal women '13 Nov 1990'". Justia Patents. Retrieved 11 June 2015. 
  6. ^ Hutkin, Erinn (7 January 2014). "Hormone therapies help older adults find new life". UT San Diego. 
  7. ^ Langille, Jane (20 March 2014). "Low T: Separating Facts From Frenzy low-testosterone". MedShadow. 
  8. ^ Florence Comite, Janet Baek. "Hormonal Expression of Androgen Decline in Aging Men (ADAM)". Male Reproductive Endocrinology & Case Reports Clinical. The Endocrine Society. Retrieved 15 June 2013. 
  9. ^ Editor (13 December 2013). "Late Nights with Jim Bohannon". The Jim Bohannon Show. 
  10. ^ Dunkel, Tom (January 15, 2010). "Vigor Quest". New York Times Magazine. Retrieved 2 April 2014. 
  11. ^ a b School, Florence Comite, MD ; Foreword by Abraham Morgentaler, MD associate clinical professor of urology, Harvard Medical (2013). Keep it up : the power of precision medicine to conquer low T and revitalize your life. Rodale Books. p. 291. ISBN 978-1609611019. 
  12. ^ Libov, Charlotte (9 October 1994). "An Aging Generation Looks for Answers". New York Times. Retrieved 2 April 2014. 
  13. ^ Tucker, Bill (15 November 2013). "WSJ's What's News - Male Menopause". Wall Street Journal Online. Retrieved 2 April 2014. 
  14. ^ a b Urist, Jacoba (21 October 2013). "Men Have Biological Clocks, Too". The Atlantic. Retrieved 2 April 2014. 
  15. ^ a b Curtis, John (11 December 2013). "Florence Comite, M.D.'76, recognized for hormone research". Yale Alumni Journal. Retrieved 2 April 2014. 
  16. ^ Comite, Florence; Cutler, Gordon B.; Rivier, Jean; Vale, Wylie W.; Loriaux, D. Lynn; Crowley, William F. (24 December 1981). "Short-Term Treatment of Idiopathic Precocious Puberty with a Long-Acting Analogue of Luteinizing Hormone-Releasing Hormone". New England Journal of Medicine. 305 (26): 1546–1550. doi:10.1056/NEJM198112243052602. PMID 6458765. 
  17. ^ Sonis, William A; Florence Comite; ORA H. PESCOVITZ; KAREN HENCH; CHARLES W. RAHN; GORDON B. CUTLER Jr.; D L LORIAUX; ROBERT P. KLEIN (28 May 1985). "Biobehavioral Aspects of Precocious Puberty". Journal of the American Academy of Child Psychiatry. 25 (5): 674–679. doi:10.1016/s0002-7138(09)60293-4. PMID 3760417. 
  18. ^ Prevention, Committee on the Use of Complementary and Alternative Medicine by the American Public, Board on Health Promotion and Disease (2004). Complementary and alternative medicine in the United States ([Online-Ausg.] ed.). Washington, DC: National Academies Press. p. 321. ISBN 978-0-309-09270-8. 
  19. ^ Richards, Avis. "Balance Documentary". Birds Nest Foundation. Retrieved 2 April 2014. 
  20. ^ "New York Superdoctors" (PDF). Independent Doctors of New York: IDNY.org. 19 May 2013. Retrieved 2 April 2014. 
  21. ^ "Alpha Omega Alpha". Directory. Alpha Omega Alpha. Retrieved 2 April 2014. 
  22. ^ "Comite C.V" (PDF). Retrieved 2 April 2014. 
  23. ^ Comite, Florence; Fernando Cassorla; Kevin M. Barnes; Karen D. Hench; Andrew Dwyer; Marilyn C. Skerda; D. Lynn Loriaux; Gordon B. Cutler Jr; Ora H. Pescovitz (16 May 1986). "Luteinizing Hormone Releasing Hormone Analogue Therapy for Central Precocious Puberty". Journal of the American Medical Association. 2613-2616. 255 (19): 2613. doi:10.1001/jama.1986.03370190097031. Retrieved 2 April 2014. 
  24. ^ Comite, Florence. "Endocrine Press". The Endocrine Society. Retrieved 2 April 2014.