|AHFS/Drugs.com||International Drug Names|
|Chemical and physical data|
|Molar mass||358.21 g/mol|
|3D model (Jmol)|
|(what is this?)|
In the United States, florfenicol is currently indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Pasteurella multocida, and Haemophilus somnus, for treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.
Florfenicol is also used in aquaculture, and is licensed for use in the United States for the control of enteric septicemia in catfish.
Since the early 2000s, it is used in Europe , treating mainly primary or secondary colibacillosis in broiler  and parent flocks. It is not allowed in laying hens, due to residues in eggs. It is also indicated in turkey.
The use of florfenicol in horses, and likely in other equids, typically causes diarrhea. This has been anecdotally reported to progress to lethal cases of acute colitis. Therefore, use of this antimicrobial in the equine patient should be limited to cases in which other, safer, options are not available.
Florfenicol was among the drug contaminants in a brand of supermarket eggs in Taiwan and Iran.
- Syriopoulou VP, Harding AL, Goldmann DA, Smith AL (February 1981). "In vitro antibacterial activity of fluorinated analogs of chloramphenicol and thiamphenicol.". Antimicrob Agents Chemother. 19 (2): 294–7. PMC . PMID 6957162.
- Gaunt, P. S.; Langston, C.; Wrzesinski, C.; Gao, D.; Adams, P.; Crouch, L.; Sweeney, D.; Endris, R. "Multidose pharmacokinetics of orally administered florfenicol in the channel catfish ( )". Journal of Veterinary Pharmacology and Therapeutics. 36 (5): 502–506. doi:10.1111/j.1365-2885.2012.01426.x.
- Shen, J.; Wu, X.; Jiang, H. "Pharmacokinetics of florfenicol in healthy and Escherichia coli-infected broiler chickens". Research in Veterinary Science. 73 (2): 137–140.
- Robinson, N.E.; Sprayberry, K.A. (2009). Current therapy in equine medicine. Saunders Elesevier. p. 13. ISBN 978-1-4160-5475-7. Retrieved March 21, 2011.
- Lee I-chia (8 January 2013). "Survey suggests certain eggs may be dangerous". Taipei Times. Retrieved 3 November 2014.