Fludroxycortide

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Fludroxycortide
Fludroxycortide.svg
Clinical data
Trade namesCordran, Haelan
Synonyms6α-Fluoro-16α-hydroxyhydrocortisone 16,17-acetonide; 6α-Fluoro-11β,16α,17α,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide
AHFS/Drugs.comMicromedex Detailed Consumer Information
Routes of
administration
Topical
ATC code
Legal status
Legal status
  • UK: POM (Prescription only)
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard100.014.724 Edit this at Wikidata
Chemical and physical data
FormulaC24H33FO6
Molar mass436.514 g/mol
3D model (JSmol)
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Fludroxycortide (INN, BAN, JAN), also known as flurandrenolide (USAN) and flurandrenolone,[1] is a synthetic topical corticosteroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).[2][3]

Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses.[4][5]

References[edit]

  1. ^ CID 15209 from PubChem
  2. ^ Drugs.com: Fludroxycortide
  3. ^ Patient.info: Fludroxycortide
  4. ^ Haelan Tape Summary of Product Characteristics
  5. ^ Nakamura, H.; Motoyoshi, S.; Ishii, K.; Seto, Y.; Shimizu, M. (1980). "Anti-inflammatory activity of a topical glucocorticoid, fludroxycortide tape in experimental animals (author's transl)". Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 76 (7): 595–607. PMID 7215997.