Formimidoyltransferase cyclodeaminase

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formimidoyltransferase cyclodeaminase
2pfd.jpg
Formiminotransferase cyclodeaminase homooctamer, Rattus norvegicus
Identifiers
SymbolFTCD
NCBI gene10841
HGNC3974
OMIM606806
RefSeqNM_006657
UniProtO95954
Other data
EC number4.3.1.4
LocusChr. 21 q22.3
Search for
StructuresSwiss-model
DomainsInterPro

Formimidoyltransferase cyclodeaminase or formiminotransferase cyclodeaminase (symbol FTCD in humans) is an enzyme that catalyzes the conversion of formiminoglutamate and tetrahydrofolate into formiminotetrahydrofolate and glutamate.

Role in pathology[edit]

Mutations of the FTCD gene cause glutamate formiminotransferase deficiency. [1]

See also[edit]

References[edit]

  1. ^ "Glutamate formiminotransferase deficiency". NIH. GARD. August 10, 2016. Retrieved December 21, 2020.

External links[edit]