Fraley syndrome

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Fraley syndrome is a condition where the superior infundibulum of the upper calyx of the kidney is obstructed by the crossing renal (upper or middle section) artery branch, causing distension and dilatation of the calyx and presenting clinically as haematuria and nephralgia (ipsilateral flank pain).[1][2][3] The condition was first described by urologist Elwin E. Fraley in 1966 and can be treated surgically, which might be necessary in symptomatic disease.[4][5] Another possible cause for similar hydronephrosis is megacalicosis, for which surgery is considered inappropriate.[6]

See also[edit]


  1. ^ "Fraley's syndrome". Whonamedit. Retrieved 2011-09-19. [unreliable medical source?]
  2. ^ Zuckier LS, Patel YD, Fine EJ, Koenigsberg M (1988). "Fraley's syndrome: case report and update on current diagnostic methods". Urologic Radiology. 10 (2): 103–6. doi:10.1007/BF02926548. PMID 3055628. 
  3. ^ "Fraley syndrome -". 2011-08-23. Retrieved 2011-09-19. [unreliable medical source?]
  4. ^ D'Amico A, Lusuardi L, Ficarra V, et al. (October 2000). "Experience in the surgical treatment of Fraley's syndrome". European Urology. 38 (4): 410–4. doi:10.1159/000020316. PMID 11025378. 
  5. ^ Benz G, Willich E (1977). "Upper calyx reno-vascular obstruction in children: Fraley's syndrome". Pediatric Radiology. 5 (4): 213–8. doi:10.1007/BF00972180. PMID 263509. 
  6. ^ O'Reilly PH (August 1989). "Relationship between intermittent hydronephrosis and megacalicosis". British Journal of Urology. 64 (2): 125–9. doi:10.1111/j.1464-410X.1989.tb05970.x. PMID 2670046.