|Frances Hamilton Arnold|
|Alma mater||Princeton University, University of California, Berkeley, Caltech|
Garvan–Olin Medal (2005)|
FASEB Excellence in Science Award (2007)
Draper Prize (2011)
National Medal of Technology and Innovation (2013)
Raymond and Beverly Sackler Prize in Convergence Research (2017)
|Notable students||Christopher Voigt, Huimin Zhao|
Frances Hamilton Arnold (born 25 July 1956) is an American scientist and engineer. She pioneered methods of directed evolution to create useful biological systems, including enzymes, metabolic pathways, genetic regulatory circuits, and organisms. She is the Linus Pauling Professor of Chemical Engineering, Bioengineering, and Biochemistry at the California Institute of Technology, where she studies evolution and its applications in science, medicine, chemicals and energy. She earned her B.S. in Mechanical and Aerospace Engineering from Princeton University in 1979 and her Ph.D. in Chemical Engineering from the University of California, Berkeley. There, she did her postdoctoral work in biophysical chemistry before coming to Caltech in 1986.
Her work has been recognized by many awards, including the 2011 Draper Prize and a 2013 National Medal of Technology and Innovation. She was elected to the American Academy of Arts and Sciences in 2011. Arnold has the rare honor of being elected to all three National Academies in the United States - The National Academy of Sciences, The National Academy of Engineering, and the Institute of Medicine. Arnold is a Fellow of the American Association for the Advancement of Science, the American Academy of Arts and Sciences, the American Academy of Microbiology, the American Institute for Medical and Biological Engineering and an International Fellow of the Royal Academy of Engineering in the UK.
A member of the Advisory Board of the DOE-funded Joint BioEnergy Institute and the Packard Fellowships in Science and Engineering, Arnold also serves on the President's Advisory Council of the King Abdullah University of Science and Technology (KAUST). She is currently serving as a judge for The Queen Elizabeth Prize for Engineering.
Arnold's Caltech research is in green chemistry and alternative energy, including the development of highly active enzymes (cellulolytic and biosynthetic enzymes) and microorganisms to convert renewable biomass to fuels and chemicals. She is co-inventor on numerous patents and co-founded Gevo, Inc. in 2005.
In 2016 she became the first woman to win the Millennium Technology Prize, which she won for pioneering directed evolution. In 2017, Arnold was awarded the Raymond and Beverly Sackler Prize in Convergence Research by the National Academy of Sciences, which recognizes extraordinary contributions to convergence research.
Arnold is the daughter of nuclear physicist William Howard Arnold and grew up in Edgewood, Pennsylvania, a small suburb of Pittsburgh. As a high schooler, she hitchhiked to Washington, D.C. to protest the Vietnam War and lived on her own working as a cocktail waitress at a local jazz club and a cab driver.
- Elected an International Fellow of the Royal Academy of Engineering (2018)
- Society of Women Engineers' 2017 Achievement Award 
- Honorary Degree of Doctor of Science from Dartmouth College (2017)
- Millennium Technology Prize (2016)
- Honorary Degree of Doctor of Science from the ETH Zurich (2015)
- Inducted into the National Inventors Hall of Fame (2014)
- Emanuel Merck Lecture of the Technische Universität Darmstadt, Germany (2013)
- National Medal of Technology and Innovation (2013)
- ENI award (2013)
- Charles Stark Draper Prize (2011)
- Enzyme Engineering Award from Engineering Conferences International and Genencor (2007)
- President Obama Honors Nation's Top Scientists and Innovators 
- Newsmakers, Science, Volume 320, Number 5878, 16 May 2008 
- M. Goho "Cellulolytic Enzymes: Frances Arnold is designing better enzymes for making biofuels from cellulose. "
- 10 Emerging Technologies 2008, Cellulolytic enzymes, Technology Review, p. 52, March/April 2008.
- "Caltech Professor Frances H. Arnold Elected to the National Academy of Sciences". Caltech. 2008-05-05.
- "Evolutionary engineer Frances Arnold wins €1m tech prize - BBC News". Bbc.com. Retrieved 2016-05-25.
- "2017 Raymond and Beverly Sackler Prize in Convergence Research". National Academy of Sciencces. Retrieved 2017-03-11.
- Kharif, Olga (March 15, 2012). "Frances Arnold's Directed Evolution". Bloomberg Businessweek. Retrieved 1 September 2012.
- Hamilton, Walter (July 3, 2011). "Frances Arnold: Career path of a Caltech scientist". Los Angeles Times. Retrieved 1 September 2012.
- "50 engineering leaders become Fellows of the Royal Academy of Engineering". Retrieved 21 September 2018.
- "Pioneer of "Directed Evolution" Wins Lifetime Achievement Award | Caltech". The California Institute of Technology. Retrieved 2017-08-31.
- "Frances Arnold (Doctor of Science)". Dartmouth College. June 11, 2017. Retrieved June 11, 2017.
- "Evolutionary engineer Francis Arnold wins €1m tech prize". May 25, 2016. Retrieved May 25, 2016.
- "Doing the right things". ETH Zurich. November 21, 2015. Retrieved November 23, 2015.
- "Spotlight | National Inventors Hall of Fame". Invent.org. 2013-11-21. Retrieved 2016-05-28.
- "PRESS RELEASE: President Obama Honors Nation's Top Scientists and Innovators". whitehouse.gov. 2012-12-21. Retrieved 2016-05-25.
- "Frances H. Arnold, Enzyme Engineering Award for 2007". www.engconf.org. Retrieved 2018-06-21.
- "Archived copy". Archived from the original on August 29, 2008. Retrieved May 1, 2009.
- Top Stories (2008-02-19). "TR10: Cellulolytic Enzymes - MIT Technology Review". Technologyreview.com. Retrieved 2016-05-25.
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