He trained together with Giuseppe Rusconi in Rome. Here he executed the statues of St. Charles Borromeo and St. Bernard in the façade of Santa Maria Maggiore, a bust of Christine of Sweden (1740), the statue of "Autumn" in the Trevi Fountain (1749) and the sepulchre of Duchess Grillo in Sant'Andrea delle Fratte (1752).
After 1752 he was active in the decoration of the famed Neapolitan Cappella Sansevero.
Release from Deception (Il Disinganno) produced in 1752-59 – this statue shows a fisherman being released from a net by an angel. The masterpiece was carved from a single piece of marble and can be seen in Capella San Severo, Naples. The project was so ambitious and considered even impossible to be completed, so from all masters in the country only Francesco was brave enough to agree on doing it.
- "Release from Deception by QUEIROLO, Francesco". www.wga.hu.
- Wittkower, Rudolf (1993). "Art and Architecture Italy, 1600-1750". Pelican History of Art. 1980. Penguin Books. pp. 449–450.
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