Villamena was born in Assisi. He studied under Cornelis Cort. Others state he was a follower of Agostino Carracci. Villamena produced primarily works of religious and historical subjects. He died in Rome in 1624.
- Milizia, Francesco (1797). Dizionario delle Belle Arti del Disegno y Estratto in Gran Parte dalla Enciclopedia Metodica da Francesco Milizia, Seconda Edizione, Tomo Secondo. Bassano, Italy. p. 18.