He made several pioneer contributions to British neurophysiology. With his brother-in-law, Victor Horsley (1857–1916), he performed research involving localization of brain function via electrical stimulation of the cortex, and also demonstrated that the mammalian brain was capable of producing electric current.
In 1891, with Horsley, he delivered the Croonian Lecture before the Royal Society of London, entitled "On The Mammalian Nervous System: Its Functions, And Their Localization Determined By An Electrical Method". In June 1892 he was elected a Fellow of the Royal Society 
- Classics in the History of Psychology
- Ian Glynn (2000). An Anatomy of Thought. Oxford University Press US. ISBN 0-19-515803-2.
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