Francis Peyton Rous
|Francis Peyton Rous|
Francis Peyton Rous
|Born||October 5, 1879
|Died||February 16, 1970
New York City
|Alma mater||Johns Hopkins University, Johns Hopkins School of Medicine|
|Notable awards||National Medal of Science (1965)
Nobel Prize in Physiology or Medicine (1966)
He born in Woodlawn, Maryland in 1879 and received his B.A. and M.D. from Johns Hopkins University. He was involved in the discovery of the role of viruses in the transmission of certain types of cancer. In 1966 he was awarded a Nobel Prize in Physiology or Medicine for his work.
In 1911, as a pathologist he made his seminal observation, that a malignant tumor (specifically, a sarcoma) growing on a domestic chicken could be transferred to another fowl simply by exposing the healthy bird to a cell-free filtrate. This finding, that cancer could be transmitted by a virus (now known as the Rous sarcoma virus, a retrovirus), was widely discredited by most of the field's experts at that time. Since he was a relative newcomer, it was several years before anyone even tried to replicate his prescient results. Although clearly some influential researchers were impressed enough to nominate him to the Nobel Committee as early as 1926 (and in many subsequent years, until he finally received the award, 40 years later—this may be a record for the time between a discovery and a Nobel Prize).
- Harald zur Hausen - German virologist who discovered the role of papilloma virus as a cause of cervical cancer.
- Cornwall, Claudia M. Catching cancer : the quest for its viral and bacterial causes. Lanham: Rowman & Littlefield Publishers, 2013.
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- Rous, Peyton (1910). "A Transmissible Avian Neoplasm (Sarcoma of the Common Fowl)". Journal of Experimental Medicine 12 (5): 696–705. doi:10.1084/jem.12.5.696. PMC 2124810. PMID 19867354.
- Rous, Peyton (1911). "A Sarcoma of the Fowl Transmissible by an Agent Separable from the Tumor Cells". Journal of Experimental Medicine 13 (4): 397–411. doi:10.1084/jem.13.4.397. PMC 2124874. PMID 19867421.
- Rous, P. (1949). "Simon Flexner. 1863-1946". Obituary Notices of Fellows of the Royal Society 6 (18): 408–426. doi:10.1098/rsbm.1949.0006.
- Rous, P. (1947). "Karl Landsteiner. 1868-1943". Obituary Notices of Fellows of the Royal Society 5 (15): 294–226. doi:10.1098/rsbm.1947.0002.
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- "Francis Peyton Rous, M.D. Johns Hopkins". Lancet 1 (7644): 477. 1970. PMID 4189793.
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- Datta, R. K.; Datta, B. (1967). "Nobel prize winners in medicine". Journal of the Indian Medical Association 48 (1): 41–42. PMID 5342283.
- Graffi, A. (1966). "Francis Peyton Rous". Deutsche medizinische Wochenschrift (1946) 91 (51): 2309–2310. PMID 5333372.
- Kreyberg, L. (1966). "Nobel prize in physiology and medicine 1966 (Rous FP)". Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 86 (22): 1565. PMID 4859882.
- "Nobel Prize". BMJ 2 (5520): 964–961. 1966. doi:10.1136/bmj.2.5520.964.
- Rhoads, C. P. (1959). "Citation and presentation of the Academy Medal to F. Peyton Rous". Bulletin of the New York Academy of Medicine 35 (4): 216–219. PMC 1806149. PMID 13629203.