Fluckiger was in charge of the CERN external network. He contributed to the creation of CCIRN (Coordinating Committee for Intercontinental Research Network), RIPE (Réseaux IP Européens) and Ebone (European Backbone).
After the departure of Tim Berners-Lee from CERN, François Fluckiger took over him to lead the web development technical team at CERN. He chaired the Inet1988, Inet2001 and Inet2002 conference programme.
Between 2001-2011 he was an OpenLab manager and until 2013 he held the position of the Director of the CERN School of Computing. He is Knowledge and Technology Transfer Officer for Information Technologies at CERN. He is a lecturer at the University of Geneva, a member of the Internet Society Advisory Council and of the W3C Advisory Committee.
- F.Fluckiger Understanding Networked Multimedia, Prentice Hall, 1995, ISBN 0-13-190992-4
- F.Fluckiger "The European Research Network", Translated from "Les Réseau des Chercheurs Européens ", La Rechecrhe, February 2000
- F.Fluckiger "CERN Celebrates Another Key Contribution to the Internet", CERN Computer Newsletter, June 29, 2009
- "People: François Flückiger joins Internet Hall of Fame". CERN Courier. 53 (7): 58. September 2013.
- Olivier Martin,“The “hidden” Prehistory of European Research Networking”, E-Book, Trafford Publishing, June 2012[self-published source]
- Howard Davies and Beatrice Bressan,“A History of International Research Networking”, Wiley-Blackwell", February 2010
- Dave Raggett, “My involvement with the early days of the Web”, W3C 10th Anniversary Conference, Boston, December 2004
- James Gillies, Robert Cailliau, “How the Web Was Born – The Story of the World Wide Web”, Oxford University Press, September 2000
- Internet Society, Past INET conferences, Official list
- Fluckiger, François (May 2012). "The openlab adventure continues to thrive". CERN Courier. 52 (4): 37–39.
- Fluckiger, François (December 2013). "CERN School of Computing: 10 years of renewal". CERN Courier. 53 (10): 15–17.