Frank Burr Mallory

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Frank Burr Mallory
Frank Burr Mallory.jpg
Frank Burr Mallory, from the American Journal of Pathology, 1933
Born12 November 1862
DiedSeptember 27, 1941(1941-09-27) (aged 78)
NationalityUnited States
Alma materHarvard College (1886)
Harvard Medical School (1890) [1]
Known forpathology, Mallory body
Scientific career
InstitutionsBoston City Hospital

Frank Burr Mallory (1862–1941) was an American pathologist at the Boston City Hospital and Professor of Pathology at Harvard Medical School, after whom the Mallory body is named.[2]

The Pathology Department at Boston City Hospital, the Mallory Institute of Pathology, was named after him.[1]

Early life and career[edit]

He was born in Cleveland, Ohio on 12 November 1862 to George Burr and Anne (Faragher) Mallory, and received his medical degree in 1890 from Harvard Medical School. He became an assistant pathologist at Boston City Hospital in 1891, working under William Thomas Councilman.

He married Persis McClain Tracy of Chautauqua, New York in 1893.[3]

In 1893 he traveled to Europe to train under Hans Chiari in Prague and Ernst Ziegler in Freiburg.

After returning to Harvard, he became an Assistant Professor in 1896, and Associate Professor of Pathology in 1901. He became Professor of Pathology at Harvard Medical School from 1928 to 1932.

His contributions in the field of pathology included improving techniques and standardisation of tissue staining; his book, written with James Homer Wright, was the standard textbook in this field.[4] He also studied the function of histiocytes, he confirmed that the whooping cough bacillus discovered by Jules Bordet was the causative agent, and he worked on improvements in classification of tumours, particularly meningiomas, and cirrhosis of the liver.

He was president of the American Association of Pathologists and Bacteriologists in 1910, and was its treasurer from 1911 to 1940. He was the editor of the Journal of Medical Research from 1923, and then founding editor of the American Journal of Pathology from 1925 to 1940.

Honors and awards[edit]

Mallory received honorary degrees from Tufts University (Sc.D., 1928) and Boston University (Sc.D., 1932), and was awarded the Kober medal in 1935 by the Association of American Physicians for outstanding service in pathology.


He died in Boston on September 27, 1941, at the age of 78.[1]

He had two sons, both of whom were medical doctors and pathologists.[3] Tracy B. Mallory, was Chief of Pathology at Massachusetts General Hospital in Boston, succeeding James Homer Wright in 1926,[5] and president of the American Association of Pathologists and Bacteriologists in 1951. His other son, George Kenneth Mallory, became Professor of Pathology at Boston City Hospital in 1948, and the Mallory-Weiss syndrome is named after him.[6]


  1. ^ a b c Parker, F. "Frank Burr Mallory". Am J Pathol. 17 (6): i4–786. PMC 1965288. PMID 19970606.
  2. ^ Jensen, K; Gluud, C (Oct 1994). "The Drew Parlin body: morphological, clinical and experimental studies (Part 1 of a literature survey)". Hepatology. 20 (4 Pt 1): 1061–77. doi:10.1002/hep.1840200440. PMID 7927209.
  3. ^ a b Haythorn, Samuel R., "Frank Burr Mallory. 1862–1941, The Journal of Pathology and Bacteriology, Volume 54, Issue 2, pages 263–267, April 1942
  4. ^ Frank B. Mallory, James H. Wright. Pathological Technique : a practical manual for workers in pathological histology and bacteriology : including directions for the performance of autopsies and for clinical diagnosis by laboratory methods. First published 1897
  5. ^ "History of Pathology at MGH", Massachusetts General Hospital Pathology Department website
  6. ^ Stedman, Thomas Lathrop (2005). Stedman's Medical Eponyms. Baltimore: Lippincott Williams and Wilkins. p. 450. ISBN 0781754437.

Further reading[edit]

  • Louis, David N.; Young, Robert H., (editors), Keen minds to explore the dark continents of disease : a history of the pathology services at Massachusetts General Hospital", Boston, Mass. : Massachusetts General Hospital, 2011. ISBN 9780615486383