Friedrich Loeffler

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Friedrich August Johannes Loeffler
Friedrich August Johannes Loeffler
Born24 June 1852
Died9 April 1915 (aged 62)
Alma materUniversity of Würzburg
University of Berlin
Known forCorynebacterium diphtheriae
Scientific career
InstitutionsUniversity of Greifswald
Friedrich Loeffler Institute
InfluencesRobert Koch

Friedrich August Johannes Loeffler (German: [ˈlœflɐ]; 24 June 1852 – 9 April 1915) was a German bacteriologist at the University of Greifswald.


He obtained his M.D. degree from the University of Berlin in 1874. He worked with Robert Koch from 1879 to 1884[1] as an assistant in the Imperial Health Office in Berlin. In 1884, he became staff physician at the Friedrich Wilhelm Institute in Berlin, and four years later became professor at the University of Greifswald.[2]

His development of original methods of staining rendered an important and lasting service to bacteriology.[2] Early in his career, he began a study of parasitic diseases.[3] Among his discoveries was the organism causing diphtheria (Corynebacterium diphtheriae) and the cause of foot-and-mouth disease (Aphthovirus). His description of the diphtheria bacillus, published in 1884, was the originating cause of an antitoxin treatment.[3] He also created Löffler's serum, a coagulated blood serum used for the detection of the bacteria. In 1887, he founded the Zentralblatt für Bakteriologie und Parasitik.[2]

The Friedrich Loeffler Institute on the Isle of Riems near Greifswald, as well as the Friedrich Loeffler Institute of Medical Microbiology at the Greifswald Medical School of the University of Greifswald, have been named in his honor.


  1. ^ Isaac Asimov, Asimov's Biographical Encyclopedia of Science and Technology, 2nd Revised edition
  2. ^ a b c Rines, George Edwin, ed. (1920). "Loeffler, Friedrich" . Encyclopedia Americana.
  3. ^ a b Chisholm, Hugh, ed. (1922). "Löffler, Friedrich" . Encyclopædia Britannica (12th ed.). London & New York: The Encyclopædia Britannica Company.


  • Bochalli R (January 1959). "Friedrich Loeffler, his life & works; on the occasion of 75th return of the anniversary of the discovery of the diphtheria bacillus". Medizinische Monatsschrift. 13 (1): 59–62. PMID 13632391.
  • Howard DH (July 1963). "Friedrich LOEFFLER and the Thessalian field mouse plague of 1892". Jornal de historia da medicina. 18 (3): 272–81. doi:10.1093/jhmas/xviii.3.272. PMID 13955107.
  • Kaiser G (1965). "Friedrich Loeffler zum 80. Geburtstag" [Friedrich Loeffler on his 80th birthday]. Archiv für orthopädische und Unfall-Chirurgie. 58 (2): 85–7. doi:10.1007/BF00416118. PMID 5327173. S2CID 28053507.
  • Matiner HR (1967). "Nachruf für Friedrich Loeffler" [In memory of Friedrich Loeffler]. Archiv für orthopädische und Unfall-Chirurgie. 62 (4): 269–72. doi:10.1007/BF00416209. PMID 4875506. S2CID 41107594.
  • Blencke B (August 1967). "In memory of Professor Friedrich Loeffler". Zeitschrift für Orthopädie und ihre Grenzgebiete. 103 (3): 273–6. PMID 4233465.
  • "Friedrich Loeffler (1852–1915). Klebs-Loeffler bacillus". JAMA. 210 (6): 1096–7. 10 November 1969. doi:10.1001/jama.210.6.1096. PMID 4898725.
  • Hauck P (1978). "Opening address of the scientific festive colloquium commemorating the 125th birthday of Friedrich Loeffler on June 21st and 22d, 1977 in Greifswald". Archiv für experimentelle Veterinärmedizin. 32 (3): 311–2. PMID 29591.
  • Hüller H, Berndt HG, Dittrich M (1978). "The work of Friedrich Loeffler in Greifswald". Archiv für experimentelle Veterinärmedizin. 32 (3): 313–8. PMID 358941.
  • Bethge R, Knöfler EW (May 1983). "30 years of the East Germany Orthopedic Society—in memory of its co-founder and 1st chairman Friedrich Loeffler". Beiträge zur Orthopädie und Traumatologie. 30 (5): 233–6. PMID 6349609.
  • Beer J (September 1985). "Friedrich Loeffler as a founder of virology". Archiv für experimentelle Veterinärmedizin. 39 (5): 623–30. PMID 3907574.
  • Mochmann H, Köhler W (1990). "Friedrich Loeffler (1852–1915)--his contributions to bacteriology and virology. In memory of the 75th anniversary of his death". Zeitschrift für ärztliche Fortbildung. 84 (8): 400–6. PMID 2198709.
  • Wittmann W, Lafer EM (2002). "Friedrich Loeffler's way to the Isle of Riems near Greifswald". Historia medicinae veterinariae. 27 (1–4): 217–30. PMID 12506922.

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