Fungal mating pheromone receptors

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Fungal pheromone mating factor STE2 GPCR
PDB 1pjd EBI.jpg
Structure of a Peptide Segment of the 6th Transmembrane Domain of the Saccharomyces cerevisiae alpha-Factor Receptor.[1]
Symbol STE2
Pfam PF02116
InterPro IPR000366
SCOP 1pjd
OPM superfamily 6
OPM protein 2k9p

Fungal pheromone mating factor receptors form a distinct family of G-protein-coupled receptors.


Mating factor receptors STE2 and STE3 are integral membrane proteins that may be involved in the response to mating factors on the cell membrane.[2][3][4] The amino acid sequences of both receptors contain high proportions of hydrophobic residues grouped into 7 domains, in a manner reminiscent of the rhodopsins and other receptors believed to interact with G-proteins.