Furoxan

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Furoxan
Furoxan.png
Names
IUPAC name
1,2,5-Oxadiazole 2-oxide
Other names
Furazan N-oxide; Furazan 2-oxide
Identifiers
3D model (JSmol)
ChemSpider
MeSH C528141
Properties
C2H2N2O2
Molar mass 86.05 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Furoxan or 1,2,5-oxadiazole 2-oxide is a heterocycle of the isoxazole family and an amine oxide derivative of furazan. It is a nitric oxide donor.[1] As such, furoxan and its derivatives are actively researched as potential new drugs and insensitive high density explosives. Ipramidil is an example.

Furoxanes can be formed by dimerization of nitrile oxides.

References[edit]

  1. ^ Clara Cena; Massimo Bertinaria; Donatella Boschi; Marta Giorgis; Alberto Gasco (2006). "Use of the furoxan (1,2,5-oxadiazole 2-oxide) system in the design of new NO-donor antioxidant hybrids" (PDF). Arkivoc (HL-1787GR): 301–309.