|Preferred IUPAC name
3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||179.219 g·mol−1|
|Melting point||97 to 98 °C (207 to 208 °F; 370 to 371 K)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
It is typically isolated from various Fusarium species, and has been proposed for a various therapeutic applications. However, it is primarily used as a research tool.
Its mechanism of action is not well understood. It likely inhibits Dopamine beta-hydroxylase (the enzyme that converts dopamine to norepinephrine). It may also have other actions, such as the inhibition of cell proliferation and DNA synthesis. Fusaric acid and analogues also reported as quorum sensing inhibitors.
It is used to make bupicomide.
- Yabuta et al., J. Agric. Chem. Soc. Jpn. 10, 1059 (1934).
- Tung et al., Eur. J. Med. Chem. dx.doi.org/10.1016/j.ejmech.2016.11.044.
- Media related to Fusaric acid at Wikimedia Commons