Fuselloviridae is a family of viruses. Sulfolobus species, specifically shibatae, solfataricus, and islandicus, serve as natural hosts. There are currently nine species in this family, divided among 2 genera. The Fuselloviridae are ubiquitous in high-temperature (≥70 °C), acidic (pH ≤4) hot springs around the world. They are one of the few viruses to possess a lipid membrane and a protective inner capsid in the form of a core.
Viral replication is cytoplasmic. Entry into the host cell is achieved by adsorption into the host cell. Dna templated transcription is the method of transcription. Sulfolobus shibatae, sulfolobus solfataricus, and sulfolobus islandicus serve as the natural host.