GABRG1

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GABRG1
Identifiers
Aliases GABRG1
External IDs MGI: 103156 HomoloGene: 22570 GeneCards: GABRG1
Targeted by Drug
picrotoxin[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_173536

NM_010252

RefSeq (protein)

NP_775807

NP_034382.2
NP_034382

Location (UCSC) Chr 4: 46.04 – 46.12 Mb Chr 5: 70.75 – 70.84 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Gamma-aminobutyric acid receptor subunit gamma-1 is a protein that in humans is encoded by the GABRG1 gene.[4] The protein encoded by this gene is a subunit of the GABAA receptor.[5]

Variants of this gene may be associated with alcohol dependence.[6]

References[edit]

  1. ^ "Drugs that physically interact with Gamma-aminobutyric acid type A receptor gamma1 subunit view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Wilcox AS, Warrington JA, Gardiner K, Berger R, Whiting P, Altherr MR, Wasmuth JJ, Patterson D, Sikela JM (July 1992). "Human chromosomal localization of genes encoding the gamma 1 and gamma 2 subunits of the gamma-aminobutyric acid receptor indicates that members of this gene family are often clustered in the genome". Proc. Natl. Acad. Sci. U.S.A. 89 (13): 5857–61. doi:10.1073/pnas.89.13.5857. PMC 49396Freely accessible. PMID 1321425. 
  5. ^ Hevers W, Lüddens H (August 1998). "The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes". Mol. Neurobiol. 18 (1): 35–86. doi:10.1007/BF02741459. PMID 9824848. 
  6. ^ Ittiwut C, Listman J, Mutirangura A, Malison R, Covault J, Kranzler HR, Sughondhabirom A, Thavichachart N, Gelernter J (January 2008). "Interpopulation linkage disequilibrium patterns of GABRA2 and GABRG1 genes at the GABA cluster locus on human chromosome 4". Genomics. 91 (1): 61–9. doi:10.1016/j.ygeno.2007.08.007. PMC 2709929Freely accessible. PMID 17976953. 

Further reading[edit]

External links[edit]