GABRP

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GABRP
Identifiers
Aliases GABRP, gamma-aminobutyric acid type A receptor pi subunit
External IDs MGI: 2387597 HomoloGene: 22798 GeneCards: GABRP
RNA expression pattern
PBB GE GABRP 205044 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001291985
NM_014211

NM_146017

RefSeq (protein)

NP_001278914
NP_055026

NP_666129.1
NP_666129

Location (UCSC) Chr 5: 170.76 – 170.81 Mb Chr 11: 33.55 – 33.58 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Gamma-aminobutyric acid receptor subunit pi is a protein that in humans is encoded by the GABRP gene.[3][4]

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.[4]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Hedblom E, Kirkness EF (Jul 1997). "A novel class of GABAA receptor subunit in tissues of the reproductive system". J Biol Chem. 272 (24): 15346–50. doi:10.1074/jbc.272.24.15346. PMID 9182563. 
  4. ^ a b "Entrez Gene: GABRP gamma-aminobutyric acid (GABA) A receptor, pi". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.