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Gamma-aminobutyric acid (GABA) A receptor, pi
Symbols GABRP ; MGC126386; MGC126387
External IDs OMIM602729 MGI2387597 HomoloGene22798 IUPHAR: 419 ChEMBL: 3506 GeneCards: GABRP Gene
RNA expression pattern
PBB GE GABRP 205044 at tn.png
More reference expression data
Species Human Mouse
Entrez 2568 216643
Ensembl ENSG00000094755 ENSMUSG00000020159
UniProt O00591 Q8QZW7
RefSeq (mRNA) NM_001291985 NM_146017
RefSeq (protein) NP_001278914 NP_666129
Location (UCSC) Chr 5:
170.76 – 170.81 Mb
Chr 11:
33.55 – 33.58 Mb
PubMed search [1] [2]

Gamma-aminobutyric acid receptor subunit pi is a protein that in humans is encoded by the GABRP gene.[1][2]

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.[2]

See also[edit]


  1. ^ Hedblom E, Kirkness EF (Jul 1997). "A novel class of GABAA receptor subunit in tissues of the reproductive system". J Biol Chem 272 (24): 15346–50. doi:10.1074/jbc.272.24.15346. PMID 9182563. 
  2. ^ a b "Entrez Gene: GABRP gamma-aminobutyric acid (GABA) A receptor, pi". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.