GAL3ST1

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GAL3ST1
Identifiers
Aliases GAL3ST1, CST, galactose-3-O-sulfotransferase 1
External IDs MGI: 1858277 HomoloGene: 3574 GeneCards: GAL3ST1
RNA expression pattern
PBB GE GAL3ST1 205670 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001177691
NM_001177703
NM_016922

RefSeq (protein)
Location (UCSC) Chr 22: 30.55 – 30.57 Mb Chr 11: 3.98 – 4 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Galactosylceramide sulfotransferase is an enzyme that in humans is encoded by the GAL3ST1 gene.[3][4][5]

Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. Jan 1999. doi:10.1101/gr.8.11.1097. PMID 9847074. 
  4. ^ Honke K, Tsuda M, Hirahara Y, Ishii A, Makita A, Wada Y (Apr 1997). "Molecular cloning and expression of cDNA encoding human 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase". J Biol Chem. 272 (8): 4864–8. doi:10.1074/jbc.272.8.4864. PMID 9030544. 
  5. ^ a b "Entrez Gene: GAL3ST1 galactose-3-O-sulfotransferase 1". 

Further reading[edit]