GALNT13

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GALNT13
Identifiers
Aliases GALNT13, GalNAc-T13, polypeptide N-acetylgalactosaminyltransferase 13
External IDs MGI: 2139447 HomoloGene: 62167 GeneCards: GALNT13
Genetically Related Diseases
obesity[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001301627
NM_052917

NM_173030

RefSeq (protein)

NP_001288556
NP_443149

NP_766618.2
NP_766618

Location (UCSC) Chr 2: 153.87 – 154.45 Mb Chr 2: 54.44 – 55.12 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Polypeptide N-acetylgalactosaminyltransferase 13 is an enzyme that in humans is encoded by the GALNT13 gene.[4][5][6]

The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM][6]

References[edit]

  1. ^ "Diseases that are genetically associated with GALNT13 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Nagase T, Kikuno R, Ohara O (Sep 2001). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins". DNA Res. 8 (4): 179–87. doi:10.1093/dnares/8.4.179. PMID 11572484. 
  5. ^ Zhang Y, Iwasaki H, Wang H, Kudo T, Kalka TB, Hennet T, Kubota T, Cheng L, Inaba N, Gotoh M, Togayachi A, Guo J, Hisatomi H, Nakajima K, Nishihara S, Nakamura M, Marth JD, Narimatsu H (Dec 2002). "Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen". J Biol Chem. 278 (1): 573–84. doi:10.1074/jbc.M203094200. PMID 12407114. 
  6. ^ a b "Entrez Gene: GALNT13 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)". 

Further reading[edit]