GANAB

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GANAB
Identifiers
Aliases GANAB, G2AN, GLUII, GIIA, glucosidase II alpha subunit, PKD3
External IDs MGI: 1097667 HomoloGene: 5426 GeneCards: GANAB
Gene location (Human)
Chromosome 11 (human)
Chr. Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for GANAB
Genomic location for GANAB
Band 11q12.3 Start 62,624,826 bp[1]
End 62,646,726 bp[1]
RNA expression pattern
PBB GE GANAB 214626 s at fs.png

PBB GE GANAB 211934 x at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001293621
NM_008060

RefSeq (protein)

NP_001280550
NP_032086

Location (UCSC) Chr 11: 62.62 – 62.65 Mb Chr 11: 8.9 – 8.92 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Neutral alpha-glucosidase AB is an enzyme that in humans is encoded by the GANAB gene.[5][6][7]

Interactions[edit]

GANAB has been shown to interact with PTPRC.[8][9][10]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000089597 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000071650 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Treml K, Meimaroglou D, Hentges A, Bause E (May 2000). "The alpha- and beta-subunits are required for expression of catalytic activity in the hetero-dimeric glucosidase II complex from human liver". Glycobiology. 10 (5): 493–502. PMID 10764838. doi:10.1093/glycob/10.5.493. 
  6. ^ Martiniuk F, Smith M, Ellenbogen A, Desnick RJ, Astrin K, Mitra J, Hirschhorn R (July 1983). "Assignment of the gene for neutral alpha-glucosidase AB to chromosome 11". Cytogenet Cell Genet. 35 (2): 110–6. PMID 6342981. doi:10.1159/000131851. 
  7. ^ "Entrez Gene: GANAB glucosidase, alpha; neutral AB". 
  8. ^ Arendt CW, Ostergaard HL (May 1997). "Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II". J. Biol. Chem. 272 (20): 13117–25. PMID 9148925. doi:10.1074/jbc.272.20.13117. 
  9. ^ Baldwin TA, Gogela-Spehar M, Ostergaard HL (October 2000). "Specific isoforms of the resident endoplasmic reticulum protein glucosidase II associate with the CD45 protein-tyrosine phosphatase via a lectin-like interaction". J. Biol. Chem. 275 (41): 32071–6. PMID 10921916. doi:10.1074/jbc.M003088200. 
  10. ^ Baldwin TA, Ostergaard HL (October 2001). "Developmentally regulated changes in glucosidase II association with, and carbohydrate content of, the protein tyrosine phosphatase CD45". J. Immunol. 167 (7): 3829–35. PMID 11564800. doi:10.4049/jimmunol.167.7.3829. 

Further reading[edit]