GANAB

From Wikipedia, the free encyclopedia
Jump to: navigation, search
GANAB
Identifiers
Aliases GANAB, G2AN, GLUII, GIIA, glucosidase II alpha subunit
External IDs MGI: 1097667 HomoloGene: 5426 GeneCards: 23193
RNA expression pattern
PBB GE GANAB 211934 x at tn.png

PBB GE GANAB 214626 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001293621
NM_008060

RefSeq (protein)

NP_001265121.1
NP_001265122.1
NP_001265123.1
NP_938148.1
NP_938149.2

NP_001280550.1
NP_032086.1

Location (UCSC) Chr 11: 62.62 – 62.65 Mb Chr 19: 8.9 – 8.92 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Neutral alpha-glucosidase AB is an enzyme that in humans is encoded by the GANAB gene.[3][4][5]

Interactions[edit]

GANAB has been shown to interact with PTPRC.[6][7][8]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Treml K, Meimaroglou D, Hentges A, Bause E (May 2000). "The alpha- and beta-subunits are required for expression of catalytic activity in the hetero-dimeric glucosidase II complex from human liver". Glycobiology. 10 (5): 493–502. doi:10.1093/glycob/10.5.493. PMID 10764838. 
  4. ^ Martiniuk F, Smith M, Ellenbogen A, Desnick RJ, Astrin K, Mitra J, Hirschhorn R (July 1983). "Assignment of the gene for neutral alpha-glucosidase AB to chromosome 11". Cytogenet Cell Genet. 35 (2): 110–6. doi:10.1159/000131851. PMID 6342981. 
  5. ^ "Entrez Gene: GANAB glucosidase, alpha; neutral AB". 
  6. ^ Arendt CW, Ostergaard HL (May 1997). "Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II". J. Biol. Chem. 272 (20): 13117–25. doi:10.1074/jbc.272.20.13117. PMID 9148925. 
  7. ^ Baldwin TA, Gogela-Spehar M, Ostergaard HL (October 2000). "Specific isoforms of the resident endoplasmic reticulum protein glucosidase II associate with the CD45 protein-tyrosine phosphatase via a lectin-like interaction". J. Biol. Chem. 275 (41): 32071–6. doi:10.1074/jbc.M003088200. PMID 10921916. 
  8. ^ Baldwin TA, Ostergaard HL (October 2001). "Developmentally regulated changes in glucosidase II association with, and carbohydrate content of, the protein tyrosine phosphatase CD45". J. Immunol. 167 (7): 3829–35. doi:10.4049/jimmunol.167.7.3829. PMID 11564800. 

Further reading[edit]