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GBR or GbR may refer to:
- Great Barrier Reef, off the coast of Queensland, Australia
- United Kingdom, by ISO 3166-1 code
- Walter J. Koladza Airport, also known as the Great Barrington Airport, a privately owned airport in Great Barrington, Massachusetts, United States open to the public by IATA airport code
- GBR (subpixels) (Green, Blue, Red), an RGB display pixel layout
- Guided bone regeneration, a medical procedure
- Gerber format, a file format with extension gbr
- Guaranteed Bit Rate, a characteristic of LTE network traffic flows
- GbR, (German: Gesellschaft bürgerlichen Rechts), a type of business entity in Germany
- Great Britain at the Olympics, by IOC country code
- GBR compound, nomenclature code for a series of molecular drugs that are congeners with benztropine
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