GCSS may refer to:
- Game Critter Super-Squad! (GCSS), a comic strip
- GEWEX Cloud System Study (GCSS), a meteorological study
- Global Combat Support System (GCSS), a framework for managing military logistics
- Global Combat Support System-Army (GCSS-A)
- Grand Cross of the Order of St. Sylvester, a class in one of the orders of knighthood of the Holy See
disambiguation page lists articles associated with the title GCSS.
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