GDF1

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GDF1
Identifiers
Aliases GDF1, DORV, DTGA3, RAI, growth differentiation factor 1
External IDs OMIM: 602880 MGI: 95683 HomoloGene: 105644 GeneCards: GDF1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001492

NM_001163282
NM_008107

RefSeq (protein)

NP_001483

NP_001156754.1
NP_032133.2
NP_001156754
NP_032133

Location (UCSC) Chr 19: 18.87 – 18.9 Mb Chr 8: 70.33 – 70.33 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Growth differentiation factor-1 (GDF1) is a protein that in humans is encoded by the GDF1 gene.[3]

GDF1 belongs to the transforming growth factor beta superfamily that has a role in left-right patterning and mesoderm induction during embryonic development.[4] It is found in the brain, spinal cord and peripheral nerves of embryos.[3][4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ a b Lee SJ (May 1991). "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure". Proc. Natl. Acad. Sci. U.S.A. 88 (10): 4250–4. PMC 51636Freely accessible. PMID 2034669. doi:10.1073/pnas.88.10.4250. 
  4. ^ a b Rankin CT, Bunton T, Lawler AM, Lee SJ (March 2000). "Regulation of left-right patterning in mice by growth/differentiation factor-1". Nat. Genet. 24 (3): 262–5. PMID 10700179. doi:10.1038/73472. 

Further reading[edit]