GENSCAN

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GENSCAN
Developer(s) Christopher Burge
Available in English
Type Bioinformatics tool
Website genes.mit.edu/GENSCANinfo.html

In bioinformatics GENSCAN is a program to identify complete gene structures in genomic DNA. It is a GHMM-based program that can be used to predict the location of genes and their exon-intron boundaries in genomic sequences from a variety of organisms. The GENSCAN Web server can be found at MIT.[1]

GENSCAN was developed by Christopher Burge [2] in the research group of Samuel Karlin [3][4] Department of Mathematics, Stanford University.

References[edit]

  1. ^ http://genes.mit.edu/GENSCAN.html The GENSCAN Web Server at MIT
  2. ^ Burge, C. B. (1998) Modeling dependencies in pre-mRNA splicing signals. In Salzberg, S., Searls, D. and Kasif, S., eds. Computational Methods in Molecular Biology, Elsevier Science, Amsterdam, pp. 127-163. ISBN 978-0-444-50204-9
  3. ^ Burge, Christopher; Karlin, Samuel (1997). "Prediction of complete gene structures in human genomic DNA" (PDF). Journal of Molecular Biology 268 (1): 78–94. doi:10.1006/jmbi.1997.0951. PMID 9149143. 
  4. ^ Burge, C.; Karlin, S. (1998). "Finding the genes in genomic DNA" (PDF). Current Opinion in Structural Biology 8 (3): 346–354. doi:10.1016/S0959-440X(98)80069-9. PMID 9666331.