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The GDNF family receptor-α (GFRα) proteins are a group of co-receptors which form complexes with GDNF-family ligands (GFLs) to activate RET, the receptor of the GFLs. The GFRα co-receptors include the following:
- GFRα1 – preference for GDNF
- GFRα2 – preference for neurturin
- GFRα3 – preference for artemin
- GFRα4 – preference for persephin
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