GJA10

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GJA10
Identifiers
Aliases GJA10, CX62, gap junction protein alpha 10
External IDs MGI: 1339969 HomoloGene: 7733 GeneCards: GJA10
Targeted by Drug
carbenoxolone, flufenamic acid, caprylic alcohol[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_032602

NM_010289

RefSeq (protein)

NP_115991

NP_034419.2
NP_034419

Location (UCSC) Chr 6: 89.89 – 89.9 Mb Chr 4: 32.6 – 32.6 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Gap junction alpha-10 protein, also known as connexin-62 (Cx62), is a protein that in humans is encoded by the GJA10 gene.[4]

Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[4][5]

References[edit]

  1. ^ "Drugs that physically interact with Gap junction protein alpha 10 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ a b "Entrez Gene: gap junction protein". 
  5. ^ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.