Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. For a general discussion of connexin proteins, see GJB2.
In melanocytic cells GJB1 gene expression may be regulated by MITF.
Hattori N, Yamamoto M, Yoshihara T; et al. (2003). "Demyelinating and axonal features of Charcot-Marie-Tooth disease with mutations of myelin-related proteins (PMP22, MPZ and Cx32): a clinicopathological study of 205 Japanese patients.". Brain126 (Pt 1): 134–51. doi:10.1093/brain/awg012. PMID12477701.
Sato H, Hagiwara H, Ohde Y; et al. (2007). "Regulation of renal cell carcinoma cell proliferation, invasion and metastasis by connexin 32 gene.". J. Membr. Biol.216 (1): 17–21. doi:10.1007/s00232-007-9020-5. PMID17565422.