GJB7

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GJB7
Identifiers
Aliases GJB7, CX25, bA136M9.1, connexin25, gap junction protein beta 7
External IDs HomoloGene: 89311 GeneCards: GJB7
Targeted by Drug
carbenoxolone, flufenamic acid, caprylic alcohol[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_198568

n/a

RefSeq (protein)

NP_940970

n/a

Location (UCSC) Chr 6: 87.28 – 87.33 Mb n/a
PubMed search [2] n/a
Wikidata
View/Edit Human

Gap junction beta-7 protein (GJB7), also known as connexin-25 (Cx25), is a protein that in humans is encoded by the GJB7 gene.[3]

Function[edit]

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[3][4]

References[edit]

  1. ^ "Drugs that physically interact with Gap junction protein beta 7 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ a b "Entrez Gene: gap junction protein". 
  4. ^ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.