GJD2

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GJD2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases GJD2, CX36, GJA9, gap junction protein delta 2
External IDs MGI: 1334209 HomoloGene: 7734 GeneCards: 57369
RNA expression pattern
PBB GE GJA9 221407 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020660

NM_010290

RefSeq (protein)

NP_065711.1

NP_034420.2

Location (UCSC) Chr 15: 34.75 – 34.75 Mb Chr 2: 114.01 – 114.01 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Gap junction delta-2 protein (GJD2) also known as connexin-36 (Cx36) or gap junction alpha-9 protein (GJA9) and is a protein that in humans is encoded by the GJD2 gene.[1][2]

Function[edit]

GJD2, also called connexin-36 (CX36), is a member of the connexin gene family that is expressed predominantly in mammalian neurons. Connexins associate in groups of 6 and are organized radially around a central pore to form connexons. Each gap junction intercellular channel is formed by the conjunction of 2 connexons. See GJB2 for additional background information on connexins.[2]

References[edit]

  1. ^ Belluardo N, Trovato-Salinaro A, Mudo G, Hurd YL, Condorelli DF (Oct 1999). "Structure, chromosomal localization, and brain expression of human Cx36 gene". J Neurosci Res 57 (5): 740–52. doi:10.1002/(SICI)1097-4547(19990901)57:5<740::AID-JNR16>3.0.CO;2-Z. PMID 10462698. 
  2. ^ a b "Entrez Gene: GJA9 gap junction protein, alpha 9, 36kDa". 

Further reading[edit]