GJD3

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GJD3
Identifiers
Aliases GJD3, CX31.9, Cx30.2, GJA11, GJC1, gap junction protein delta 3
External IDs MGI: 2384150 HomoloGene: 17530 GeneCards: GJD3
Gene location (Human)
Chromosome 17 (human)
Chr. Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for GJD3
Genomic location for GJD3
Band 17q21.2 Start 40,362,931 bp[1]
End 40,363,815 bp[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_152219

NM_178596

RefSeq (protein)

NP_689343

NP_848711

Location (UCSC) Chr 17: 40.36 – 40.36 Mb Chr 17: 98.98 – 98.98 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Gap junction delta-2 (GJD2), also known as connexin-36 (Cx36) or gap junction alpha-9 (GJA9), is a protein that in humans is encoded by the GJD2 gene.[5]

Function[edit]

This gene is a member of the large family of connexins that are required for the formation of gap junctions. Six connexin monomers form a hemichannel, or connexon, on the cell surface. This connexon can interact with a connexon from a neighboring cell, thus forming a channel linking the cytoplasm of the 2 cells.[5]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.