GLRB

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
GLRB
Protein GLRB PDB 1t3e.png
Identifiers
Aliases GLRB, HKPX2, glycine receptor beta
External IDs MGI: 95751 HomoloGene: 20224 GeneCards: GLRB
Gene location (Human)
Chromosome 4 (human)
Chr. Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for GLRB
Genomic location for GLRB
Band 4q32.1 Start 157,076,057 bp[1]
End 157,172,090 bp[1]
RNA expression pattern
PBB GE GLRB 205280 at fs.png

PBB GE GLRB 205279 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000824
NM_001166060
NM_001166061

RefSeq (protein)

NP_000815
NP_001159532
NP_001159533

Location (UCSC) Chr 4: 157.08 – 157.17 Mb Chr 3: 80.84 – 80.91 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Glycine receptor subunit beta is a protein that in humans is encoded by the GLRB gene.[5][6][7]

The inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed of alpha (GLRA1, MIM 138491; GLRA2, MIM 305990) and beta subunits.[supplied by OMIM][7]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000109738 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028020 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Milani N, Mulhardt C, Weber RG, Lichter P, Kioschis P, Poustka A, Becker CM (Oct 1998). "The human glycine receptor beta subunit gene (GLRB): structure, refined chromosomal localization, and population polymorphism". Genomics. 50 (3): 341–5. doi:10.1006/geno.1998.5324. PMID 9676428. 
  6. ^ Handford CA, Lynch JW, Baker E, Webb GC, Ford JH, Sutherland GR, Schofield PR (Oct 1996). "The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes". Brain Res Mol Brain Res. 35 (1–2): 211–9. doi:10.1016/0169-328x(95)00218-h. PMID 8717357. 
  7. ^ a b "Entrez Gene: GLRB glycine receptor, beta". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.