GLRB

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"GLRB" is also the ICAO code for Roberts International Airport near Monrovia, Liberia.
GLRB
Protein GLRB PDB 1t3e.png
Identifiers
Aliases GLRB, HKPX2, glycine receptor beta
External IDs MGI: 95751 HomoloGene: 20224 GeneCards: GLRB
Targeted by Drug
bilobalide, nifedipine, pregnenolone sulfate, picrotoxin[1]
RNA expression pattern
PBB GE GLRB 205279 s at tn.png

PBB GE GLRB 205280 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000824
NM_001166060
NM_001166061

RefSeq (protein)

NP_000815
NP_001159532
NP_001159533

NP_034428.2

Location (UCSC) Chr 4: 157.08 – 157.17 Mb Chr 3: 80.84 – 80.91 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Glycine receptor subunit beta is a protein that in humans is encoded by the GLRB gene.[4][5][6]

The inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed of alpha (GLRA1, MIM 138491; GLRA2, MIM 305990) and beta subunits.[supplied by OMIM][6]

See also[edit]

References[edit]

  1. ^ "Drugs that physically interact with Glycine receptor beta view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Milani N, Mulhardt C, Weber RG, Lichter P, Kioschis P, Poustka A, Becker CM (Oct 1998). "The human glycine receptor beta subunit gene (GLRB): structure, refined chromosomal localization, and population polymorphism". Genomics. 50 (3): 341–5. doi:10.1006/geno.1998.5324. PMID 9676428. 
  5. ^ Handford CA, Lynch JW, Baker E, Webb GC, Ford JH, Sutherland GR, Schofield PR (Oct 1996). "The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes". Brain Res Mol Brain Res. 35 (1–2): 211–9. doi:10.1016/0169-328x(95)00218-h. PMID 8717357. 
  6. ^ a b "Entrez Gene: GLRB glycine receptor, beta". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.