GLRX

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GLRX
Protein GLRX PDB 1b4q.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases GLRX, GRX, GRX1, glutaredoxin
External IDs MGI: 2135625 HomoloGene: 37566 GeneCards: 2745
RNA expression pattern
PBB GE GLRX 206662 at tn.png

PBB GE GLRX 209276 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002064
NM_001118890
NM_001243658
NM_001243659

NM_053108

RefSeq (protein)

NP_001112362.1
NP_001230587.1
NP_001230588.1
NP_002055.1

NP_444338.2

Location (UCSC) Chr 5: 95.75 – 95.82 Mb Chr 13: 75.84 – 75.85 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene.[1][2]


Interactions[edit]

GLRX has been shown to interact with Wilson disease protein[3] and ATP7A.[3]

References[edit]

  1. ^ Padilla CA, Bajalica S, Lagercrantz J, Holmgren A (Feb 1997). "The gene for human glutaredoxin (GLRX) is localized to human chromosome 5q14". Genomics 32 (3): 455–7. doi:10.1006/geno.1996.0141. PMID 8838810. 
  2. ^ "Entrez Gene: GLRX glutaredoxin (thioltransferase)". 
  3. ^ a b Lim, Chris M; Cater Michael A; Mercer Julian F B; La Fontaine Sharon (Sep 2006). "Copper-dependent interaction of glutaredoxin with the N termini of the copper-ATPases (ATP7A and ATP7B) defective in Menkes and Wilson diseases". Biochem. Biophys. Res. Commun. (United States) 348 (2): 428–36. doi:10.1016/j.bbrc.2006.07.067. ISSN 0006-291X. PMID 16884690. 

Further reading[edit]