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Adhesion G protein-coupled receptor D2
Symbols ADGRD2 ; GPR144; PGR24
External IDs HomoloGene130029 IUPHAR: GeneCards: ADGRD2 Gene
RNA expression pattern
PBB GE GPR144 gnf1h05191 x at tn.png
More reference expression data
Species Human Mouse
Entrez 347088 n/a
Ensembl ENSG00000180264 n/a
UniProt Q7Z7M1 n/a
RefSeq (mRNA) NM_001161808 n/a
RefSeq (protein) NP_001155280 n/a
Location (UCSC) Chr 9:
127.21 – 127.24 Mb
PubMed search [1] n/a

Probable G-protein coupled receptor 144 is a protein that in humans is encoded by the GPR144 gene.[1][2] This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterised by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.[3][4]


  1. ^ "Entrez Gene: GPR144 G protein-coupled receptor 144". 
  2. ^ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett 531 (3): 407–14. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584. 
  3. ^ Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 1-4419-7912-3. 
  4. ^ Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC 3321182. PMID 22333914. 

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