GPR177

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WLS
Identifiers
Aliases WLS, C1orf139, EVI, GPR177, MRP, mig-14, wntless Wnt ligand secretion mediator
External IDs MGI: 1915401 HomoloGene: 11779 GeneCards: 79971
RNA expression pattern
PBB GE GPR177 221958 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001002292
NM_001193334
NM_024911

NM_026582

RefSeq (protein)

NP_001002292.3
NP_001180263.1
NP_079187.3

NP_080858.3

Location (UCSC) Chr 1: 68.1 – 68.23 Mb Chr 3: 159.84 – 159.94 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

G protein-coupled receptor 177 (GPR177), commonly known as Wntless, is a human gene[1] that encodes a receptor for Wnt proteins in Wnt-secreting cells.[2]

Wntless was shown to be a cargo for the retromer complex.[2] It has been found essential for hair follicle induction.[3]

References[edit]

  1. ^ "Entrez Gene: GPR177 G protein-coupled receptor 177". 
  2. ^ a b Eaton S (January 2008). "Retromer retrieves wntless". Dev. Cell. 14 (1): 4–6. doi:10.1016/j.devcel.2007.12.014. PMID 18194646. 
  3. ^ Fu, J.; Hsu, W. (2012). "Epidermal Wnt Controls Hair Follicle Induction by Orchestrating Dynamic Signaling Crosstalk between the Epidermis and Dermis". Journal of Investigative Dermatology 133 (4): 890–8. doi:10.1038/jid.2012.407. PMID 23190887. 

Further reading[edit]

See also[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.